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Antibacterial Activity of Vernonia amygdalina and Vernonia cinerea Leaf Extracts through Microwave-Assisted Extraction Technique

Authors: Alara OR, Abdurahman NH, Ukaegbu CI, Osazuwa OU

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The occurrence of multi-drug-resistant bacteria has been a great challenge facing public health care in recent times. Therefore, this study investigated the antibacterial activity of extracts from two species of Vernonia (Vernonia amygdalina and Vernonia cinerea) against Bacillus cereus, Enterococcus faecalis, Pseudomonas aeruginosa, and Escherichia coli. The results obtained showed that the tested bacteria were sensitive to extracts from both plant samples in the concentration range of 6 to 30 mg/mL. Higher sensitivities were seen at a concentration of 30 mg/mL. Moreover, the sensitivities were more in the extract from V. amygdalina leaf as compared to V. cinerea leaf extract. In addition, the minimum inhibitory concentration (MIC) showed a higher susceptibility of B. cereus and P. aeruginosa to V. amygdalina and V. cinerea leaves extracts, respectively. The plant extracts exhibited antibacterial effects against the tested organisms with a potential of being used as antibiotics.

Affiliations: Department of Chemical Engineering, Faculty of Engineering, University of Benin, PMB 1154, Benin City, Edo State, Nigeria.
Keywords: Vernonia Amygdalina Leaf, Antibacterial Activity, Vernonia Cinerea Leaf, Extraction, Inhibition
Published date: 2022/12/30

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ISSN: 2635-3342 (Print)

ISSN: 2635-3350 (Online)

DOI: In progress

ISI Impact Factor: In progress

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Chemical Engineering Department, Faculty of Engineering, University of Benin, PMB 1154, Ugbowo, Benin City, Edo State, Nigeria.