Antimicrobial Efficacy of Zingiber officinale (Ginger) Extract on Candida albicans and Streptococcus viridans

Authors: Saidu JZ, Olannye PG, Orhibabor GO, Ahonsi CO, Emoghene AO

DOI Info: N/A

ABSTRACT

This research work was carried out to investigate the phytochemical constituents and antimicrobial efficacy of Ginger (Zingiber officinale) extract on Streptococcus viridans and Candida albicans. The rhizome of Ginger (Zingiber officinale) plant were collected and identified in the Department of Plant Biology and Biotechnology, University of Benin. Screening for the presence of alkaloids, tannins, flavonoids, saponins, glycoside and carbohydrate was carried out using standard method. The microbial strains used in the study were obtained from University of Benin Teaching Hospital (UBTH) and re-identified using conventional methods. Standard microbiological methods were adopted for antimicrobial susceptibility testing using different concentrations of ginger extract from 12.5 % to 100 %. Standard antibiotics were used to determine the susceptibility to the bacterial isolates. The multiple antibiotic resistance (MAR) index was deduced from the antibiogram to evaluate the public health importance of the strain. The results revealed that alkaloids, saponins, cardiac glycosides and flavonoids were present in the methanolic extract of ginger. At 100% concentration, Streptococcus viridans had 22.00±0.00 mm zone of inhibition. At the same concentration, Candida albicans was found to be resistant to the ginger extract. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of ginger extract against S. viridans were at a concentration of 50 %. C. albicans although resistant to ginger extract was found to be susceptible to fluconazole at a concentration of 100 ?g/ml. The MAR index revealed that the bacterial strains were obtained from sources were antibiotics have been used and they are of public health importance.

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